HAIM COHEN'S LAB
For the Molecular Mechanisms of Aging
Our lab explores the basic biological mechanisms underlying aging. We search for new approaches to delay and prevent aging-associated diseases, particularly metabolic dysfunctions. All under our vision of increasing knowledge and improving the world.
Get to know us
Publications
Podcasts
Longevity by Design
Modern Healthspan
Longevity by Design
Longevity.Technology
Longevity.Technology
In the news
Feldman-Trabelsi, S., Touitou, N., Nagar, R. et al. The mammalian longevity associated acetylome. Nat Commun 16, 3749 (2025)
Touitou, N., Lerrer, B. & Cohen, H.Y. It is a branched road to adipose tissue aging. Nat Aging 3, 911–912 (2023).
Roichman, A., Elhanati, S., Aon, M.A. et al. Restoration of energy homeostasis by SIRT6 extends healthy lifespan. Nat Commun 12, 3208 (2021).
Naiman, S., Huynh, F. K., Gil, R., Glick, Y., Shahar, Y., Touitou, N., Nahum, L., Avivi, M. Y., Roichman, A., Kanfi, Y., Gertler, A. A., Doniger, T., Ilkayeva, O. R., Abramovich, I., Yaron, O., Lerrer, B., Gottlieb, E., Harris, R. A., Gerber, D., Hirschey, M. D., & Cohen, H. Y. (2019). SIRT6 promotes hepatic β-oxidation via activation of PPARα to protect against diet-induced fatty liver disease. Cell Reports, 29(11), 3799–3811.e9.
Kanfi, Y., Naiman, S., Amir, G. et al. The sirtuin SIRT6 regulates lifespan in male mice. Nature 483, 218–221 (2012).